2,614 research outputs found

    A survey on the evolution of the notion of context-awareness

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    The notion of Context has been considered for a long time in different areas of Computer Science. This article considers the use of context-based reasoning from the earlier perspective of AI as well as the newer developments in Ubiquitous Computing. Both communities have been somehow interested in the potential of context-reasoning to support real-time meaningful reactions from systems. We explain how the concept evolved in each of these different approaches. We found initially each of them considered this topic quite independently and separated from each other, however latest developments have started to show signs of cross-fertilization amongst these areas. The aim of our survey is to provide an understanding on the way context and context-reasoning were approached, to show that work in each area is complementary, and to highlight there are positive synergies arising amongst them. The overarching goal of this article is to encourage further and longer-term synergies between those interested in further understanding and using context-based reasoning

    Is Context-aware Reasoning = Case-based Reasoning?

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    The purpose of this paper is to explore the similarities and differences and then argue for the potential synergies between two methodologies, namely Context-aware Reasoning and Case-based Reasoning, that are amongst the tools which can be used for intelligent environment (IE) system development. Through a case study supported by a review of the literature, we argue that context awareness and case based reasoning are not equal and are complementary methodologies to solve a domain specific problem, rather, the IE development paradigm must build a cooperation between these two approaches to overcome the individual drawbacks and to maximise the success of the IE systems

    Programming Skeletal Muscle Metabolic Flexibility in Offspring of Male Rats in Response to Maternal Consumption of Slow Digesting Carbohydrates during Pregnancy

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    Skeletal muscle plays a relevant role in metabolic flexibility and fuel usage and the associated muscle metabolic inflexibility due to high-fat diets contributing to obesity and type 2 diabetes. Previous research from our group indicates that a high-fat and rapid-digesting carbohydrate diet during pregnancy promotes an excessive adipogenesis and also increases the risk of non-alcoholic fatty liver disease in the offspring. This effect can be counteracted by diets containing carbohydrates with similar glycemic load but lower digestion rates. To address the role of the skeletal muscle in these experimental settings, pregnant rats were fed high-fat diets containing carbohydrates with similar glycemic load but different digestion rates, a high fat containing rapid-digesting carbohydrates diet (HF/RD diet) or a high fat containing slow-digesting carbohydrates diet (HF/SD diet). After weaning, male offspring were fed a standard diet for 3 weeks (weaning) or 10 weeks (adolescence) and the impact of the maternal HF/RD and HF/SD diets on the metabolism, signaling pathways and muscle transcriptome was analyzed. The HF/SD offspring displayed better muscle features compared with the HF/RD group, showing a higher muscle mass, myosin content and differentiation markers that translated into a greater grip strength. In the HF/SD group, metabolic changes such as a higher expression of fatty acids (FAT/CD36) and glucose (GLUT4) transporters, an enhanced glycogen content, as well as changes in regulatory enzymes such as muscle pyruvate kinase and pyruvate dehydrogenase kinase 4 were found, supporting an increased muscle metabolic flexibility and improved muscle performance. The analysis of signaling pathways was consistent with a better insulin sensitivity in the muscle of the HF/SD group. Furthermore, increased expression of genes involved in pathways leading to muscle differentiation, muscle mass regulation, extracellular matrix content and insulin sensitivity were detected in the HF/SD group when compared with HF/RD animals. In the HF/SD group, the upregulation of the ElaV1/HuR gene could be one of the main regulators in the positive effects of the diet in early programming on the offspring. The long-lasting programming effects of the HF/SD diet during pregnancy may depend on a coordinated gene regulation, modulation of signaling pathways and metabolic flexibility that lead to an improved muscle functionality. The dietary early programming associated to HF/SD diet has synergic and positive crosstalk effects in several tissues, mainly muscle, liver and adipose tissue, contributing to maintain the whole body homeostasis in the offspring.European Union’s Seventh Framework Programme (FP7/2007–2013

    The curvature tensor of almost cosymplectic and almost Kenmotsu (\kappa,\mu,\nu)-spaces

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    We study the Riemann curvature tensor of (\kappa,\mu,\nu)-spaces when they have almost cosymplectic and almost Kenmotsu structures, giving its writing explicitly. This leads to the definition and study of a natural generalisation of the contact metric (\kappa,\mu,\nu)-spaces. We present examples or obstruction results of these spaces in all possible cases

    VirologĂ­a, epidemiologĂ­a y mecanismos de transmisiĂłn del VHB

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    Illness due to the hepatitis B virus is an enormous problem for international public health, affecting over 300 million persons throughout the world, although its prevalence varies considerably between different geographic areas. The universal vaccination of the newly born, promulgated by the World Health Organisation, has made it possible to partially control the spread of the virus in many countries, including Spain. However, the vaccine does not generate protective antibodies in approximately 5% of the population. Besides, infection by the hepatitis B virus can produce few symptoms and the virus is easily transmitted, making its epidemiological control difficult. On the other hand, the growing flow of bi-directional migration of persons between geographical areas with a moderate or high prevalence and Spain also seems to be contributing to the persistence of the disease in our milieu. All of this makes it compulsory to deploy an ensemble of preventive measures based on an increasingly deep understanding of the biological cycle of the virus. In Spain, as in other regions with a low prevalence, the hepatitis B virus infection is considered chiefly to be a disease of sexual transmission, or else contagion takes place between patients who are users of intravenous drugs. On the other hand, blood transmission is of scarce importance in our milieu. Following exposure to the hepatitis B virus, prophylaxis with immunoglobins and also the administration of the vaccine is highly effective, and acquires special interest for all healthcare workers

    Co-creation of smart technology with (and for) people with special needs

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    We report on the lessons learnt during the application of a methodology to develop Intelligent Environments. This methodology was applied to a project which aimed at helping people with Down’s Syndrome and those with similar conditions and needs, to be more included in society. The project is developed by a consortium of commercial, academic, and enduser supporting organizations. One important feature of the methodology is that of being strongly user-centred and we report on how that interaction with users took place and how it continuously shaped the projec

    The user-centred intelligent environments development process as a guide to co-create smart technology for people with special needs

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    We report on the lessons learnt during the application of a methodology to develop Intelligent Environments. One important feature of the methodology is that of being strongly user-centred and we report on how that interaction with users took place and how it continuously shaped our project aspirations and outcomes. The methodology was applied to a project which aimed at helping people with Downs Syndrome and those with similar conditions and needs, to be more included in society. The project was developed by amconsortium of commercial, academic, and end-user supporting organizations. We explain what type of stakeholders engaging activities were considered, how these were distributed along the lifetime of the project and their impact

    Open Thoracotomy and Decortication for Chronic Empyema

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    OBJECTIVES: Traditionally, chronic empyema has been treated by thoracotomy and decortication. Some recent reports have claimed similar clinical results for videothoracoscopy, but with less morbidity and mortality than open procedures. Our experience with thoracotomy and decortication is reviewed so that the results of this surgical procedure can be adequately evaluated. MATERIALS AND METHODS: From March 1992 to June 2006, 85 patients diagnosed with empyema were treated at Santo Tomás Hospital by the first author. Diagnosis of chronic empyema was based on the duration of signs and symptoms before definitive treatment and imaging findings, such as constriction of the lungs and the thoracic cage. Thirty-three patients fulfilled the criteria for chronic empyema and underwent open thoracotomy and decortication. RESULTS: Twenty-seven patients (81.8 %) were male and the average age of the study group was 34 years. The etiology was pneumonia in 26 patients (78.8%) and trauma in 7 (21.2%). The duration of symptoms and signs before definitive treatment averaged 37 days. All patients had chronic empyema, as confirmed by imaging studies and operative findings. Surgery lasted an average of 139 min. There were 3 (9%) complications with no mortality. The post-operative length of stay averaged 10 days. There were no recurrences of empyema. CONCLUSIONS: Open thoracotomy and decortication can be achieved with low morbidity and mortality. Long-term functional results are especially promising. We suggest that the validation of other surgical approaches should be based on comparative, prospective and controlled studies

    Dataset on PGA Tour tournament entry

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    This article describes a dataset that allows to explore the determinants and moderators of athletes’ decision to enter in tournaments endowed with a monetary prize. Specifically, the dataset contains variables that describe athlete's short-term momentum (i.e., performance streak in the tournaments recently entered) and long-term momentum (i.e., performance streak in the same tournament across seasons), which permits an in-depth analysis of how past performance trajectory drives self-selection into tournaments. The dataset consists of 54,915 self-selection decisions that golfers have taken over an eleven-year period (1996–2006) when deciding to participate in PGA Tour tournaments

    Regulatory parameters of self-healing alginate hydrogel networks prepared via mussel-inspired dynamic chemistry

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    Several key parameters that influence both the self-healing properties and water retention capacity of biohydrogel networks made of alginate-dopamine (Alg-DA) conjugates have been studied. A judicious combination of biopolymer concentration, dopamine content, pH-dependent cross-linking of catechol groups and the Fe3+-coordination of the networks allowed control over the self-healing ability of these bioinspired materials. Moreover, the thixotropic nature of model hydrogels was confirmed using oscillatory rheological loop tests
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